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A prospective, multicenter, open-labeled, randomized trial, the Study of Assessment for Kidney Function by Urinary Microalbumin in Randomized (SAKURA) trial, was performed in 77 clinics and hospitals in Japan (17). The trial was registered with the University Hospital Medical Information Network-Clinical Trials Registry (UMIN-CTR) under trial identification number UMIN000001247. It was approved by the Institutional Review Board of the University of Tokyo Clinical Research Center (reference number P2007028-11X) and by the review boards of all other concerned medical facilities. The implementation and data management of the trial were done by the executive office at the EBM Research Center of the Kyoto University Graduate School of Medicine. The trial was conducted in accordance with the principles of the Declaration of Helsinki. Written informed consent was obtained from all participating patients after they had received oral and written explanations about the trial.

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A prospective, multicenter, open-labeled, randomized trial, the Study of Assessment for Kidney Function by Urinary Microalbumin in Randomized (SAKURA) trial, was performed in 77 clinics and hospitals in Japan (17). The trial was registered with the University Hospital Medical Information Network-Clinical Trials Registry (UMIN-CTR) under trial identification number UMIN000001247. It was approved by the Institutional Review Board of the University of Tokyo Clinical Research Center (reference number P2007028-11X) and by the review boards of all other concerned medical facilities. The implementation and data management of the trial were done by the executive office at the EBM Research Center of the Kyoto University Graduate School of Medicine. The trial was conducted in accordance with the principles of the Declaration of Helsinki. Written informed consent was obtained from all participating patients after they had received oral and written explanations about the trial..

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